FRANCISCO JOSE TORRES DE AQUINO

@ufu.br

Professor, Chemistry
UNIVERSIDADE FEDERAL DE UBERLANDIA

FRANCISCO JOSE TORRES DE AQUINO
Graduated in Chemistry from the University of Brasília (1986), Master's in Chemistry from the University of Brasília (1991) and PhD in Organic Chemistry from the Federal University of Minas Gerais (1997). He did a postdoctoral internship (2009 and 2012) at the Laboratory of Organic and Biological Chemistry, Department of Chemistry, UFMG, under the supervision of Prof. Dr. Adão Sabino, in the area of ​​mass spectrometry. He is currently Associate Professor 4 (since September 2020) at the Federal University of Uberlândia and institutional assessor (since 2003) at the National Higher Education Assessment System (BASis) of the National Higher Education Assessment System (Sinaes), linked to the National Institute of Educational Studies and Research Anísio Teixeira (INEP), of the Ministry of Education (MEC). Has experience in the area of ​​higher education in Chemistry (since 1989), in academic research, with an emphasis on Chemistry of Natural Products, acting mainly on the following themes: mass spectrometry; coffee, essential oil and plant extracts from the Brazilian cerrado; antioxidant and antimicrobial activity; bleaching of cellulose pulps; and organic synthesis.

EDUCATION

BSc Chemistry - Universidade de Brasíli-DF/Brasil -1986
MSc Organic Chemystry - Universidade de Brasíli-DF/Brasil 1991
PhD Organic chemistry -Universidade Federal de Minas Gerais/Brasil -1997
Post-Doctoral - Universidade Federal de Minas Gerais/Brasil - 2009/2012

RESEARCH INTERESTS

Natural products
Coffee chemistry
32

Scopus Publications

901

Scholar Citations

18

Scholar h-index

24

Scholar i10-index

Scopus Publications

  • Phytochemical and in vitro antimicrobial and antidiabetical activities of Cordiera sessilis stem bark
    RODRIGO R. FRANCO, ALANNA E.A. FERREIRA, ALLISSON B. JUSTINO, JOED P. DE LIMA JÚNIOR, HEITOR C.G. SILVA, JÚLIA S. QUEIROZ, MARIANA B. SANTIAGO, MARIO M. MARTINS, ALBERTO DE OLIVEIRA, SÉRGIO A.L. MORAIS, LUIS C.S. CUNHA, CARLOS H.G. MARTINS, FRANCISCO J.T. DE AQUINO, FOUED S. ESPINDOLA
    Anais Da Academia Brasileira De Ciencias, 2025
    Studies based on medicinal plants have stood out as a complementary treatment intervention to type 2 Diabetes mellitus and its complications. Among the Brazilian medicinal plants, we highlight Cordiera sessilis (Vell.) Kuntze, in turn, has been studied in several chemical and biological studies due to its ethnopharmacological indications. Thus, this study aimed to evaluate the antimicrobial, antioxidant, antiglycation, and digestive enzyme inhibition effects of the fractions obtained from the ethanolic extract of the stem bark of C. sessilis. The results indicated that the dichloromethane, ethyl acetate, and n-butanol were the most promising fractions and therefore their phytochemical constitution was suggested by mass spectrometry. Several bioactive compounds belonging to the six classes were found, with a predominance of compounds from the flavonoid class, whose presence justifies the observed results. Thus, this study presented new results on the biological activities of this plant, contributing to the understanding of the action and effectiveness of its use in the management of diabetes mellitus and its complications.
  • Phytochemical Profiling by HPLC-ESI-MS/MS and In Vitro Investigation of the Antidiabetic Activity of Cassia bakeriana Bark Extract and Fractions
    Diego G. Prado, Allisson B. Justino, Tiara da C. Silva, Sérgio A. L. de Morais, Mário M. Martins, Paula de S. Santos, Luís C. S. Cunha, Raquel M. F. de Sousa, Francisco J. T. de Aquino, Foued S. Espindola, Alberto de Oliveira
    Journal of Mass Spectrometry, 2024
    Type 2 diabetes mellitus is a global health problem, placing patients at a higher risk of developing cardiovascular diseases and cancer. This study investigates the antidiabetic potential of Cassia bakeriana bark extracts and fractions. We evaluate their ability to inhibit α‐amylase and α‐glucosidase enzymes and advanced glycation end‐products (AGEs). The antioxidant potential was also examined. Extracts were prepared through maceration with hexane (HE) and ethanol (EE), and the fractions were obtained via liquid–liquid extraction from EE. Anti‐enzymatic, anti‐glycation, antioxidant, and cytotoxic assays were conducted in 96‐well plates using different concentrations of samples to determine the half‐maximal inhibitory concentration (IC50). Active samples were further analyzed using HPLC‐(−)‐ESI‐MS/MS. The ethyl acetate fraction (EAF) demonstrated a high percentage of α‐amylase inhibition (94.0%) with a promising IC50 value of 1.05 μg mL−1. Additionally, EAF displayed 61.5% inhibition of α‐glucosidase, with an IC50 value of 537 μg mL−1. The EE, EAF, and n‐butanol fraction (BF) exhibited strong anti‐glycation capacities. Furthermore, the EE, EAF, BF, and dichloromethane fractions showed promising antioxidant activity using the DPPH and ORAC methodologies. Cytotoxic activity was also evaluated with Vero cells, revealing no adverse effects on cell viability (CC50 > 512.0 μg mL−1). Active samples predominantly comprised proanthocyanidins, flavonoids, and anthraquinone, representing the main constituents of C. bakeriana bark. This study provides the first assessment of the antidiabetic potential of C. bakeriana bark and a comprehensive analysis of the chemical composition of its active extracts and fractions, offering hope for future treatments.
  • Antioxidant compounds from Banisteriopsis argyrophylla leaves as α-amylase, α-glucosidase, lipase, and glycation inhibitors
    Daiane M.O. Quaresma, Allisson B. Justino, Raquel M.F. Sousa, Rodrigo A.A. Munoz, Francisco J.T. de Aquino, Mário M. Martins, Luiz R. Goulart, Marcos Pivatto, Foued S. Espindola, Alberto de Oliveira
    Bioorganic Chemistry, 2020
    Banisteriopsis argyrophylla belongs to the Malpighiaceae family, which is a species from Cerrado, also known as "cipó-prata" or "cipó-folha-de-prata." Several species of this family present biological potential. This work reports the chemical identification of the ethanol extract (EE) and its fractions from B. argyrophylla leaves and shows the analysis of the antioxidant activity and inhibitory effects on activities of α-amylase, α-glucosidase and lipase, and non-enzymatic glycation. The ethyl acetate fraction (EAF) and n-butanol fraction (BF) showed antioxidant activity, with IC50 values of 4.1 ± 0.1 and 4.8 ± 0.1 μg mL-1, respectively, by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, and IC50 values of 6046.3 ± 174.2 and 6264.2 ± 32.2 µmol Trolox eq g-1 by the oxygen radical absorbance capacity (ORAC) method. Furthermore, the DPPH method with these fractions presented electroactive species with antioxidant potential, as shown by the differential pulse voltammetry (DPV) method. The inhibitory effects of the EAF and BF were demonstrated by the following results: IC50 of 5.1 ± 0.3 and 2.5 ± 0.2 μg mL-1 for α-amylase, IC50 of 1093.5 ± 26.0 and 1250.8 ± 21.9 μg mL-1 for α-glucosidase, IC50 of 8.3 ± 4.1 and 4.4 ± 1.0 μg mL-1 for lipase, and IC50 of 1.3 ± 0.1 and 0.9 ± 0.1 μg mL-1 for glycation. Some bioactive compounds were identified by (-)-ESI-MS/MS, such as catechin, procyanidins, glycosylated flavonoids, kaempferol, and megastigmane glucosides. The antidiabetic activity of B.argyrophylla has been reported for the first time.
  • Antifungal and cytotoxicity activities and new proanthocyanidins isolated from the barks of Inga laurina (Sw.) Willd
    Carla de Moura Martins, Sérgio A.L. de Morais, Mário M. Martins, Luís C.S. Cunha, Cláudio V. da Silva, Thaise Lara Teixeira, Mariana B. Santiago, Francisco J.T. de Aquino, Evandro A. Nascimento, Roberto Chang, Carlos H.G. Martins, Alberto de Oliveira
    Phytochemistry Letters, 2020
    The Inga genus comprises approximately 300 species that can be found from Mexico to northern Argentina. In folk medicine, Inga species are used to treat various diseases. The species Inga laurina is widely found in the Brazilian flora; however, there are few studies about its biological activity and chemical composition. The main purpose of this study was to identify and isolate the chemical constituents of Inga laurina barks and to evaluate the antifungal and cytotoxic activities. The total content of phenolics, proanthocyanidins, and flavonoids from the barks of Inga laurina were performed by spectrophotometric methods and the ethyl acetate (EAF) and n-butanol (BF) fractions showed the best results. Eleven compounds were identified in EAF by HPLC-ESI(−)-MS/MS, which showed good antifungal activity with MIC values of 23.4 and 46.8 μg mL−1, evaluated by broth microdilution method. Five new compounds of the genus Inga were isolated for the first time. Three of these compounds were isolated and reported on the literature for the first time: a proanthocyanidin B-type, gallocatechin-(4α→8)-4’-O-methylgallocatechin (XI) and two proanthocyanidins A-type, gallocatechin-(2→O→7,4→8)-4’-O-methylgallocatechin (XII) and gallocatechin-3-O-galloyl-(2→O→7,4→8)-4’-O-methylgallocatechin (XIII). The chemical study of the plant bark showed that this species is rich in phenolic compounds and it has great potential for the discovery of new bioactive compounds.
  • Chemical Constituents and Antileishmanial and Antibacterial Activities of Essential Oils from Scheelea phalerata
    Daiane M. Oliveira, Fabiana B. Furtado, Antoniel A. S. Gomes, Belisa R. Belut, Evandro A. Nascimento, Sérgio A. L. Morais, Carlos H. G. Martins, Vinícius C. O. Santos, Claudio V. da Silva, Thaise L. Teixeira, Luís C. S. Cunha, Alberto de Oliveira, Francisco J. T. de Aquino
    ACS Omega, 2020
    Scheelea phalerata Mart. ex Spreng (Arecaceae) is a palm tree found in the Brazilian cerrado. There are no topics related to volatile oils from S. phalerata leaves in the literature. This work determines its chemical composition and evaluates the biological activity under two different seasonal conditions (dry and rainy seasons). The dry essential oil yield was 0.034 ± 0.001% and the rainy essential oil yield was 0.011 ± 0.003%. Both essential oils presented different qualitative and quantitative compositions (99.4 and 98.5%). The main constituents of the dry essential oil were phytol (36.7%), nonadecane (9.7%), linolenic acid (9.1%), (Z)-hex-3-en-1-ol (4.2%), and squalene (4.0%). The main constituents of the rainy essential oil were phytol (26.1%), palmitic acid (18.7%), hexan-1-ol (15.6%), (Z)-hex-3-en-1-ol (9.7%), and oleic acid (4.0%). The antileishmanial activity against promastigotes of Leishmania amazonensis was observed only for the rainy season essential oil (IC50 value of 165.05 ± 33.26 μg mL–1). A molecular docking study showed that alcohols exert a paramount efficacy and that the action of some essential oil compounds may be similar to that of amphotericin B. Still, only the essential oil from the dry season showed moderate antibacterial activity against S. sanguinis (MICs 200–400 μg mL–1). The cytotoxicity against Vero cells was identical (>512) for both essential oils. The novel data here for both chemical characterization and biological activity, in particular, evidence that the action of these compounds is similar to that of amphotericin B, provide valuable information to the drug-discovery field.
  • Antimicrobial activity of seasonal essential oils from Banisteriopsis malifolia (Ness & Mart.) B. Gates
    Vanessa E. X. Martins, Evandro A. Nascimento, Luís C. S. Cunha, Carlos H. G. Martins, Thayná S. Silva, Sérgio A. L. Morais, Alberto de Oliveira, Francisco J. T. de Aquino
    Revista Virtual De Quimica, 2020
    As composicoes quimicas sazonais dos oleos das folhas de Banisteriopsis malifolia (Ness & Mart.) B. Gates foram determinadas. Terpenos (56%) e alcoois alifaticos (29,8%) estao presentes em grandes quantidades no oleo essencial da estacao chuvosa em comparacao com a estacao seca (20,93% e 20,48%, respectivamente). Por outro lado, o oleo essencial da estacao seca apresentou como compostos principais alcanos de cadeia longa (18,43%) e acidos graxos (16,03%), destacando-se o hexatriacontano (18,43%) e o acido palmitico (10,62%). O fitol foi o principal terpenoide presente em ambos os oleos essenciais (52,70% no oleo essencial das chuvas versus 15,80% no oleo essencial seco). Em geral, o oleo essencial da estacao chuvosa apresentou os melhores resultados antibacterianos (valores de MIC de 100 a 400 μg mL-1) para todas as bacterias testadas. Os efeitos sinergicos dos compostos presentes no oleo da estacao chuvosa podem ser responsaveis pelos melhores efeitos inibitorios observados. Ambos os oleos essenciais nao apresentaram nenhuma atividade anti-Candida promissora.
  • Chemical composition and bioactive potential of essential oils from banisteriopsis campestris
    Edmilson de O. Rocha, Roberto Chang, Evandro A. do Nascimento, Mário M. Martins, Sérgio A.L. de Morais, Francisco José T. de Aquino, Luís C.S. Cunha, Larissa de O. Silva, Carlos H.G. Martins, Thaise L. Teixeira, Cláudio V. da Silva, Allisson B. Justino, Foued S. Espindola
    Current Bioactive Compounds, 2020
    Background: Banisteriopsis campestris is a Malpighiaceae, also known as “cipó-prata” or “murici”. There are some reports about the use of this plant in folk medicine. Objectives: The aim of this study is to test the Essential Oils (EOs) from leaves, stems, and roots of B. campestris for antibacterial, antifungal, antioxidant, and antiprotozoal activities and the inhibition of glycation and cytotoxicity on Vero cells. Methods: The plant was collected and the essential oil was obtained and tested for antibacterial, antifungal, antioxidant, and antiprotozoal activities and the inhibition of glycation and cytotoxicity on Vero cells, using the more adequate methods to achieve the objectives. Results: The EOs inhibited the growth of aerobic and anaerobic oral bacteria. The root oil presented the highest antibacterial activity with MIC levels ranging from 12.5 to 100 μg mL-1. The three EOs showed antiprotozoal activity against Leishmania amazonensis. The stem and root EOs presented low cytotoxicity to Vero cells. The roots and stem oils showed inhibition of glycation above 50%, with stem oil with of 79.11%. The compounds identified in the leaf EOs were palmitic acid (22.98%), phytol (22.98%), and triacontane (14.88%); in the stem–palmitic (49.79%), linoleic (11.63%), oleic (4.83%), and palmitoleic (4.15%) fatty acids; in the root–palmitic acid (57.39%), linoleic (10.38%), and oleic acids (5.47%). Conclusions: The results presented indicate that the EOs have remarkable antioxidant properties and potential antimicrobial activity and confirm the essential oils of B. campestris as an alternative source of medicinal substances.
  • Chemical Composition, Antifungal, and Cytotoxicity Activities of Inga laurina (Sw.) Willd Leaves
    Carla de Moura Martins, Sérgio A. L. de Morais, Mário M. Martins, Luís C. S. Cunha, Cláudio V. da Silva, Carlos H. G. Martins, Luís F. Leandro, Alberto de Oliveira, Francisco J. T. de Aquino, Evandro A. do Nascimento, Roberto Chang
    Scientific World Journal, 2019
    The species Inga laurina is native to the Brazilian Cerrado. There are no studies about the chemical composition and biological activities of extracts of this endangered species. The ethanolic extract and its successive fractions are rich in phenolic compounds and presented good antifungal activities. HPLC/MS-MS/MS and H1/C13 analysis led to the identification of seventeen compounds, most of which are gallic acid derivatives, myricetin and quercetin glycosides. The ethyl acetate fraction (EAF) contained high levels of total phenolics, expressed in milligrams of gallic acid equivalents per gram of extract (475.3 ± 1.9 mg GAE gextract-1) and flavonoids expressed in milligrams of quercetin equivalents per gram of extract (359.3 ± 10.6 mg QE gextract-1). This fraction was active against fungi of the Candida genus. The EAF showed MIC value 11.7 μg mL−1 against C. glabrata and a selectivity index of 1.6 against Vero cells. The flavonol glycoside myricetin-3-O-rhamnoside was isolated for the first time from the Inga laurina. These results make I. laurina a promising plant as a source of pharmaceutical and biological active antifungal compounds.
  • Antifungal and cytotoxicity activities of Banisteriopsis argyrophylla leaves
    Daiane M. Oliveira, Tomás F. R. Silva, Mário M. Martins, Sérgio A. L. de Morais, Roberto Chang, Francisco J. T. de Aquino, Claudio V. da Silva, Thaise L. Teixeira, Carlos H. G. Martins, Thaís S. Moraes, Luís C. S. Cunha, Marcos Pivatto, Alberto de Oliveira
    Journal of Pharmacy and Pharmacology, 2018
    This work aimed to evaluate the antifungal and cytotoxic activity of the EtOH extract and fractions of Banisteriopsis argyrophylla leaves, and to perform the identification of these bioactive metabolites.
  • Volatile compounds obtained by the hydrodistillation of sugarcane vinasse, a residue from ethanol production
    Ana V. A. Lima, Mariana A. S. Barbosa, Luís C. S. Cunha, Sérgio A. L. de Morais, Francisco J. T. de Aquino, Roberto Chang, Evandro A. do Nascimento
    Revista Virtual De Quimica, 2017
    Sugarcane vinasse is the main by-product from ethanol production industries. Generated in large quantities, it is composed by water, inorganic and organic compounds and is extensively used as fertiliser in agriculture, promoting improvements in soil quality and crop yield. However, it has high pollution potential, as the high concentration of organic matter can lead to contamination of the soil and water, in addition to the risk of leaching of the mineral components. In the current study, the volatile components of vinasse were obtained by hydrodistillation using a Clevenger apparatus, then analysed by gas chromatography-mass spectrometry (GC-MS). A waxy material was obtained, and the GC-MS analysis indicated that vinasse is rich in fatty acids, alcohols and esters. The major components were phenylethyl alcohol (22.28%), myristic acid (17.45%), palmitic acid (15.81%), ethyl palmitate (8.99%) and hexadecanol (6.06%).
  • Bioassay-guided fractionation and antimicrobial and cytotoxic activities of cassia bakeriana extracts
    Luís C.S. Cunha, Sérgio A.L. de Morais, Francisco J.T. de Aquino, Roberto Chang, Alberto de Oliveira, Mário M. Martins, Carlos H.G. Martins, Laís C.F. Sousa, Tricya T. Barros, Cláudio V. da Silva, Evandro A. do Nascimento
    Revista Brasileira De Farmacognosia, 2017
  • Antimicrobial activity, cytotoxicity and selectivity index of Banisteriopsis laevifolia (A. Juss.) B. Gates leaves
    Bruno C. Nunes, Mário M. Martins, Roberto Chang, Sérgio A.L. Morais, Evandro A. Nascimento, Alberto de Oliveira, Luís C.S. Cunha, Claudio V. da Silva, Thaise L. Teixeira, Maria A.L.V. Ambrósio, Carlos H.G. Martins, Francisco J.T. de Aquino
    Industrial Crops and Products, 2016
  • Chemical Composition, Antimicrobial and Antiprotozoal Activity of Essential Oils From Vernonia brasiliana (Less) Druce (Asteraceae)
    Mário M. Martins, Francisco J.T. de Aquino, Alberto de Oliveira, Evandro A. do Nascimento, Roberto Chang, Mariane S. Borges, Geraldo B. de Melo, Claudio V. da Silva, Fabrício C. Machado, Sérgio A. L. de Morais
    Journal of Essential Oil Bearing Plants, 2015
  • Chemical composition, cytotoxic, and antibacterial activity of the essential oil from Eugenia calycina Cambess. leaves against oral bacteria
    Raquel Maria Ferreira Sousa, Sérgio A.L. de Morais, Raissa B.K. Vieira, Danielle R. Napolitano, Valeska B. Guzman, Thais Silva Moraes, Luís C.S. Cunha, Carlos H.G. Martins, Roberto Chang, Francisco J.T. de Aquino, Evandro A. do Nascimento, Alberto de Oliveira
    Industrial Crops and Products, 2015
  • Chemical constituents and evaluation of antimicrobial and cytotoxic activities of Kielmeyera coriacea Mart. and Zucc. essential oils
    Carla de M. Martins, Evandro A. do Nascimento, Sérgio A. L. de Morais, Alberto de Oliveira, Roberto Chang, Luís C. S. Cunha, Mário M. Martins, Carlos Henrique G. Martins, Thaís da S. Moraes, Paulla V. Rodrigues, Cláudio V. da Silva, Francisco J. T. de Aquino
    Evidence Based Complementary and Alternative Medicine, 2015
  • Direct infusion electrospray ionization mass spectrometry applied to the detection of forgeries: Roasted coffees adulterated with their husks
    Francisco J.T. Aquino, Rodinei Augusti, Júnia de O. Alves, Maria E.R. Diniz, Sérgio A.L. Morais, Blyeny H.P. Alves, Evandro A. Nascimento, Adão A. Sabino
    Microchemical Journal, 2014
  • Antioxidant activity of ora-pro-nobis (Pereskia aculeata Mill.) leaves extracts using spectrophotometric and voltammetric assays in vitro
    Bioscience Journal, 2014
  • Seasonal variation of the chemical composition and antimicrobial and cytotoxic activities of the essential oils from inga laurina (sw.) willd
    Fabiana Furtado, Francisco de Aquino, Evandro Nascimento, Carla Martins, Sérgio de Morais, Roberto Chang, Luís Cunha, Luís Leandro, Carlos Martins, Mário Martins, Claudio Silva, Fabrício Machado, Alberto de Oliveira
    Molecules, 2014
  • Organocatalysis in the three-component Povarov reaction and investigation by mass spectrometry
    Juliana Baptista Simões, Ângelo de Fátima, Adão Aparecido Sabino, Francisco José Tôrres de Aquino, Daniel Leite da Silva, Luiz Claudio Almeida Barbosa, Sergio Antonio Fernandes
    Organic and Biomolecular Chemistry, 2013
  • Essential oil composition and extracts of Cordiera sessilis (Vell.) kuntze with antioxidant and antimicrobial activity
    Latin American Journal of Pharmacy, 2013
  • Chemical composition, cytotoxic and antimicrobial activity of essential oils from cassia bakeriana craib. against aerobic and anaerobic oral pathogens
    Luís Cunha, Sérgio de Morais, Carlos Martins, Mário Martins, Roberto Chang, Francisco de Aquino, Alberto de Oliveira, Thaís Moraes, Fabrício Machado, Cláudio da Silva, Evandro do Nascimento
    Molecules, 2013
  • Chemical analysis and study of phenolics, antioxidant activity, and antibacterial effect of the wood and bark of Maclura tinctoria (L.) D. Don ex Steud.
    K. C. Lamounier, L. C. S. Cunha, S. A. L. de Morais, F. J. T. de Aquino, R. Chang, E. A. do Nascimento, M. G. M. de Souza, C. H. G. Martins, W. R. Cunha
    Evidence Based Complementary and Alternative Medicine, 2012
  • Essential oil composition and antioxidant and antimicrobial properties of Campomanesia pubescens O. Berg, native of Brazilian Cerrado
    Latin American Journal of Pharmacy, 2011
  • Bioactive compounds and antioxidant activity of conilon coffee submitted to different degrees of roasting
    Sérgio Antônio Lemos de Morais, Francisco José Tôrres de Aquino, Priscilla Mendes do Nascimento, Evandro Afonso do Nascimento, Roberto Chang
    Quimica Nova, 2009
  • Bioactive compounds, acids groups and antioxidant activity analysis of arabic coffee (Coffea arabica) and its defective beans from the Brazilian savannah submitted to different roasting degrees
    Sérgio Antônio Lemos de Morais, Francisco José Tôrres de Aquino, Evandro Afonso do Nascimento, Grasielle Silva de Oliveira, Roberto Chang, Neide Carolina dos Santos, Gabriel Marques Rosa
    Ciencia E Tecnologia De Alimentos, 2008
  • Volatiles compounds and potent odorants of conilon coffee in different degrees of roasting
    Ciencia Y Engenharia Science and Engineering Journal, 2007
  • Chemical composition of Brazilian roasted coffees from "cerrado" and south of Minas Gerais state
    Ciencia Y Engenharia Science and Engineering Journal, 2007
  • Chemical composition of conilon coffee in different degrees of roasting
    Ciencia Y Engenharia Science and Engineering Journal, 2007
  • Ozonolysis of organosolv and kraft eucalyptus lignins. Parte II: Kinetic in basic and acid media
    Quimica Nova, 1998
  • Ozonolysis of eucalyptus grandis organosolv lignin in acetic acid. Part I: functional groups analysis and molecular weight/distribution
    Ciencia and Engenharia Science and Engineering Journal, 1998
  • Cinética e anâlise de custos do branqueamento com ozônio de polpas organossolve e kraft de eucalipto
    O Papel Brazil, 1998
  • Branqueamento à baixa consistência de polpa organossolve com ozônio
    O Papel Brazil, 1997

RECENT SCHOLAR PUBLICATIONS

  • identification of three New Phenolic compounds from Ozoroa obovata (anacardiaceae) Root
    FS Silva, BF de Jesus, DA João, LCS Cunha, A de Oliveira, SAL Morais, ...
    S. Afr. J. Chem 80, S101-S105 , 2026
    2026
  • Exploring and evaluating the in vitro antifungal, antibiofilm and antitoxin efficacy of Artabotrys brachypetalus Benth. against Candida spp. and its toxicity in vivo …
    C de Paula Siqueira, R de Paula Menezes, MAS Bessa, NBS Silva, ...
    BMC Complementary Medicine and Therapies 25 (1), 258 , 2025
    2025
  • Phytochemical and in vitro antimicrobial and antidiabetical activities of Cordiera sessilis stem bark
    FJTDEAFSE RODRIGO R. FRANCO, ALANNA E.A. FERREIRA, ALLISSON B. JUSTINO, JOED ...
    ANAIS DA ACADEMIA BRASILEIRA DE CIÊNCIAS 97 (2025), 1-20 , 2025
    2025
    Citations: 2
  • Chemical Constituents and Biological Activities of Ozoroa Species: A Comprehensive Review
    DAJFJTA Frank S. da Silva, Sérgio A. L. Morais
    SOUTH AFRICAN JOURNAL OF BOTANY 179 (2025), 418-431 , 2025
    2025
    Citations: 2
  • Chemical Composition, Antioxidant Properties, and Allelopathic Activity of Coffee and Coffee Husk from the Brazilian Savanna
    FJT Andrade, A.P, Martins, C.M., Pereira, A.P., Chang, R., Terrones, M.H ...
    REVISTA OBSERVATORIO DE LA ECONOMIA LATINOAMERICANA, 1-23 , 2025
    2025
  • Volatile constituents, physicochemical properties and antibacterial activity of black and fresh garlic (Allium sativum L.)
    REVISTA OBSERVATORIO DE LA ECONOMIA LATINOAMERICANA 2 (2024), 24 , 2024
    2024
    Citations: 1
  • Phytochemical Profiling by HPLC-ESI- MS/ MS and In Vitro Investigation of the Antidiabetic Activity of Cassia bakeriana Bark Extract and Fractions
    P de S. Santos | Luís C. S. Cunha | Raquel M. F. de Sousa | Francisco J. T ...
    Journal of Mass Spectrometry 59 (2024), 1-12 , 2024
    2024
  • Chemical profile of compounds in irrigated arabica coffee by ESI-MS Perfil químico de compostos em café arábica irrigado por ESI-MS Perfil químico de compuestos en café arábica …
    Leandro Batista Machado, Sergio Antonio Lemos de Morais, Maryana Novais de ...
    REVISTA OBSERVATORIO DE LA ECONOMIA LATINOAMERICANA 22 (2024), 1 , 2024
    2024
  • MEMORIAL DESCRITIVO - PROFESSOR TITULAR
    FJTDE AQUINO
    https://repositorio.ufu.br/handle/123456789/24852 , 2023
    2023
  • TRYPANOSOMICIDAL POTENTIAL OF ESSENTIAL OILS FROM Schinus molle L.
    FJTA Nelsa P. I. Uombe, Bruna C. Borges, Frank S. da Silva, Rafael A. C ...
    46a RA SBQ 2023 , 2023
    2023
  • TRYPANOSOMICIDAL ACTIVITY OF ESSENTIAL OILS FROM Schinus molle L
    N Uombe, B Borges, S Frank, R Souza, S Morais, L Cunha, J Segovia, ...
    I WORKSHOP DE MICROBIOLOGIA E PARASITOLOGIA APLICADAS - UFU , 2022
    2022
  • Composition of the essential oil of leaves Qualea grandiflora and Qualea multiflora Mart. and antileishmanial activities
    R Chang, RR Rocha, A Oliveira, EA Nascimento, SAL Morais, FJT Aquino, ...
    Pesquisas Agrárias e Ambientais - CAPITULO 2 3, 18-27 , 2021
    2021
  • Antioxidant compounds of Kielmeyera coriacea Mart. with α-amylase, lipase and advanced glycation end-product inhibitory activities
    AB Justino, EC Santana, RR Franco, JS Queiroz, HCG Silva, ...
    Journal of Pharmaceutical and Biomedical Analysis 206, 114387 , 2021
    2021
    Citations: 9
  • Chemical composition of seasonal essential oils from Psidium myrtoides O. Berg leaves with antimicrobial, antiprotozoal, antioxidant and anti-inflammatory potential activities
    Revista virtual de Química 14 (2022), 103-114 , 2021
    2021
  • Chemical Profile and Chemometric Analysis of Genetically Modified Soybeans Produced in the Triângulo Mineiro Region (MG), Brazil
    Journal of Agricultural Studies 9 (2021), 75-95 , 2021
    2021
    Citations: 2
  • Antifungal and cytotoxicity activities and new proanthocyanidins isolated from the barks of Inga laurina (Sw.) Willd
    AO Carla Moura Martins, Sérgio A. L. Morais, Mário M. Martins, Luís C. S ...
    Phytochemistry 40 (2020), 109-120 , 2020
    2020
    Citations: 13
  • Chemical composition and bioactive potential of essential oils from Banisteriopsis campestris
    EDEO ROCHA, R CHANG, EA DO NASCIMENTO, MM MARTINS, ...
    Current Bioactive Compounds 16 (2020), 01-10, 2020. , 2020
    2020
    Citations: 3
  • Antimicrobial Activity of Seasonal Essential Oils From Banisteriopsis Malifolia (Ness & Mart.) B. Gates
    FJTA Vanessa E. X. Martins, Evandro A. Nascimento, Luís C. S. Cunha, Carlos ...
    REVISTA VIRTUAL DE QUÍMICA 12 (2020) , 2020
    2020
  • Chemical Constituents and Antileishmanial and Antibacterial Activities of Essential Oils from Scheelea phalerata
    DM Oliveira, FB Furtado, AAS Gomes, BR Belut, EA Nascimento, ...
    ACS OMEGA https://pubs.acs.org/toc/acsodf/0/0 , 2020
    2020
    Citations: 12
  • ANÁLISE ESPECTROMÉTRICA POR INFRA-VERMELHO E DO TEOR DE CINZAS DO SABÃO DE POSTOS DE LAVA A JATO DO MUNICÍPIO DE SANTA LUZIA DO PARUÁ, MA: UM ESTUDO DE CASO
    AS Lima, DG Barbalho, EKB Rodrigues, WL da Silva, FS da Silva, ...
    73ª Reunião Anual da SBPC , 2020
    2020

MOST CITED SCHOLAR PUBLICATIONS

  • Chemical Constituents and Evaluation of Antimicrobial and Cytotoxic Activities of Kielmeyera coriacea Mart. & Zucc. Essential Oils
    FJTA Carla de M. Martins, Evandro A. do Nascimento, Sérgio A. L. de Morais ...
    Evidence-Based Complementary and Alternative Medicine 2015, 1-9 , 2015
    2015
    Citations: 81
  • Chemical composition, cytotoxic, and antibacterial activity of the essential oil from Eugenia calycina Cambess. leaves against oral bacteria
    RMF Sousa, SAL de Morais, RBK Vieira, DR Napolitano, VB Guzman, ...
    Industrial Crops and Products 65, 65-78 , 2015
    2015
    Citations: 77
  • Bioactive compounds and antioxidant activity of conilon coffee submitted to different degrees of roasting
    SAL de Morais, FJT de Aquino, PM do Nascimento, EA do Nascimento, ...
    Química Nova 32, 327-331 , 2009
    2009
    Citations: 61
  • Antioxidant activity of Ora-Pro-Nobis (Pereskia aculeata Mill.) leaves extracts using spectrophotometric and voltammetric assays in vitro
    RMF SOUSA, C S. LIRA, AO RODRIGUES, SAL MORAIS, ...
    Bioscience Journal 30 ((SUPLEMENTO-1)), 448-457 , 2014
    2014
    Citations: 53
  • Chemical Analysis and Study of Phenolics, Antioxidant Activity, and Antibacterial Effect of the Wood and Bark of Maclura tinctoria (L.) D. Don ex Steud.
    KC Lamounier, LCS Cunha, SAL De Morais, FJT De Aquino, R Chang, ...
    Evidence‐Based Complementary and Alternative Medicine 2012 (1), 451039 , 2012
    2012
    Citations: 53
  • Organocatalysis in the three-component Povarov reaction and investigation by mass spectrometry
    SA Simoes, Juliana B.S., de Fatima, A., Sabino, A.A., Aquino, F. J.T., and ...
    Organic & Biomolecular Chemistry 11, 5069-5073 , 2013
    2013
    Citations: 50
  • Antimicrobial activity, cytotoxicity and selectivity index of Banisteriopsis laevifolia (A. Juss.) B.Gates leaves
    BC NUNES, MM Martins, R Chang, SAL MORAIS, EA NASCIMENTO, ...
    Industrial Crops and Products 92, 277–289 , 2016
    2016
    Citations: 48
  • Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.
    A Furtado, F.B., Aquino, F.J.T., Nascimento, E.A., Martins, C.M., Morais, S ...
    MOLECULES 19, 4560-4577 , 2014
    2014
    Citations: 41
  • Bioactive compounds, acids groups and antioxidant activity analysis of arabic coffee (Coffea arabica) and its defective beans from the Brazilian savannah submitted to different …
    SAL Morais, FJT Aquino, EA Nascimento, GS Oliveira, R Chang, ...
    Food Sci. Technol. 28, 198-207 , 2008
    2008
    Citations: 41
  • Direct Infusion Electrospray Ionization Mass Spectrometry Applied to the Detection of Forgeries: Roasted Coffees Adulterated with their Husks
    AAS Francisco J.T. Aquino, Rodinei Augusti, Júnia de O. Alves, Maria E.R ...
    Microchemical Journal 117, 127-132 , 2014
    2014
    Citations: 40
  • Bioassay-guided fractionation and antimicrobial and cytotoxic activities of Cassia bakeriana extracts
    EAN Luís C.S. Cunha, Sérgio A.L. de Morais, Francisco J.T. de Aquino ...
    Revista Brasileira de Farmacognosia 27 (1), 91-98 , 2017
    2017
    Citations: 39
  • Chemical Composition, Cytotoxic and Antimicrobial Activity of Essential Oils from Cassia bakeriana Craib. against Aerobic and Anaerobic Oral Pathogens
    LCS Cunha, SAL De Morais, CHG Martins, MM Martins, R Chang, ...
    Molecules 18 (4), 4588-4598 , 2013
    2013
    Citations: 39
  • Antifungal and cytotoxicity activities of Banisteriopsis argyrophylla leaves
    DM Oliveira, TFR Silva, MM Martins, SAL de Morais, R Chang, ...
    Journal of Pharmacy and Pharmacology 70 (11), 1541-1552 , 2018
    2018
    Citations: 28
  • Chemical Composition, Antimicrobial and Antiprotozoal Activity of Essential Oils From Vernonia brasiliana (Less) Druce (Asteraceae)
    SALM Mário M. Martins, Francisco J.T. de Aquino, Alberto de Oliveira ...
    Journal of Essential Oil Bearing Plants 18 (2015), 561 - 569 , 2015
    2015
    Citations: 23
  • Chemical analysis of arabica coffee (Coffea arabica L.) and defective beans submitted to different degrees of roasting.
    SAL Morais, FJT Aquino, R Chang, EA Nascimento, GS Oliveira, ...
    Coffee Science, Lavras 2 (2), 97-111 , 2007
    2007
    Citations: 22
  • Chemical Composition, Antifungal, and Cytotoxicity Activities of Inga laurina (Sw.) Willd Leaves
    RC Carla de Moura Martins, Sérgio A. L. de Morais, Mário M. Martins, Luís C ...
    The Scientific World Journal 2019 (2019), 1-12 , 2019
    2019
    Citations: 21
  • Essential oil composition and antioxidant and antimicrobial properties of Campomanesia pubescens O. Berg, Native of Brazilian Cerrado
    R Chang, SAL Morais, EA Nascimento, LCS Cunha, EO Rocha, ...
    Lat. Am. J. Pharm 30 (9), 1843-8 , 2011
    2011
    Citations: 21
  • Volatile compounds obtained by the hydrodistillation of sugarcane vinasse, a residue from ethanol production
    AVA Lima, MAS Barbosa, LCS Cunha, SAL de Morais, FJT de Aquino, ...
    Rev. Virtual Quim 9 (2), 764-773 , 2017
    2017
    Citations: 18
  • Chemical composition of conilon coffee in different degrees of roasting
    EA do Nascimento, FJT de Aquino, PM do Nascimento, R Chang, ...
    Ciência & Engenharia 16 (1/2), 17-21 , 2008
    2008
    Citations: 17
  • CHEMICAL COMPOSITION OF BRAZILIAN COFFEES FROM “CERRADO” AND SOUTH OF MINAS GERAIS STATE
    BHP Alves, EA do Nascimento, FJT de Aquino, R Chang, SAL de Morais
    Ciência & Engenharia 16 (1/2), 09-15 , 2008
    2008
    Citations: 16