Professor and Head of Department, Department of Paediatrics Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha
MBBS, Nagpur University, Mahatma Gandhi Institute of Medical Sciences (MGIMS), Sewagram
MD (Paediatrics ), Nagpur University, Mahatma Gandhi Institute of Medical Sciences (MGIMS), Sewagram
Fellowship in Pediatric Cardiology, Innova Children Heart Hospital, Hyderabad (2009-10).
Visiting Fellowship: Royal College of Pediatric and Child Health (RCPCH), United Kingdom (2011-12).
RESEARCH INTERESTS
Pediatric cardiology,
Neonatology
Maternal and child health
Infectious Diseases
Pediatric reserach
106
Scopus Publications
Scopus Publications
Effect of music therapy on the biophysical profile and oxygen consumption in preterm babies in a rural hospital Mahaveer Singh Lakra, Roshan Prasad, Ashwini Lakra, Amar Taksande, Revat J Meshram, Sagar Karotkar, Mayur Wanjari Chulalongkorn Medical Journal, 2026 Introduction: Music therapy in preterm babies helps in early weight gain, stabilization of heart and respiratory rates, and affect the biophysiological profile. It has a beneficial effect on oxygen consumption and hospital stay. Objectives: This study aimed to assess the effect of music therapy on biophysical profile and oxygen requirement in preterm babies. Methodology: The present comparative, observational study was carried out in the department of neonatology, a rural tertiary care hospital, Sawangi Meghe, Wardha, Maharashtra, India, for one year. All the relevant data was collected and analyzed using the prevalidated Performa. Results and observations: The male-to-female ratio both music and non-music group was 1.5 :1. The ratio of normal delivery to caesarean section was 1.2:1. The mean GA (weeks) in two groups was 31+4 and 32+5. The common aetiology in the two groups was RDS requiring CPAP. The mean birth weight in both group was 1240+112 and 1285+124 grams, respectively. The heart rate in music therapy group was 140 ± 14 vs 122 ± 8 beats/minute before and after intervention respectively. The number of days requiring oxygen was lower in music therapy group (8 vs 12). We didn’t find any significant variations in desaturation episodes, respiratory rate, oxygen saturation, blood pressure and temperature in the two groups. Conclusion: Music therapy benefit babies in the form of weight gain, stability, oxygen requirement and physiological profile rather than offering no music therapy in the NICU.
Addressing the burden of premature birth and its prevention in developing countries: is it time to act now? Mahaveer Singh Lakra, Amar Taksande, Revat J Meshram, Ashwini Lakra, Amit Kumar, Deepak Gandhi, Roshan Prasad, Mayur Wanjari Chulalongkorn Medical Journal, 2025 Around 3.5 million preterm births occur in India annually, accounting for about 25% of all preterm births worldwide. Prematurity poses a significant burden world-wide but leaves a special impact on the families and health systems of low-socioeconomic countries where easy and universal access to adequate health services is compromised. Premature birth imposes a significant risk of neonatal death among all under-fives due to organ immaturity, sepsis, and respiratory distress syndrome. Efforts to address prematurity on a global scale involve a multifaceted approach, including improving access to quality prenatal care, enhancing neonatal care services, and implementing public health interventions to reduce the infant mortality rate. Despite ongoing challenges, progress has been made in reducing the global burden of prematurity through concerted efforts by governments, international organizations, healthcare professionals, and community stakeholders. However, continued intervention, monitoring, and commitment are needed to further prevent the delivery of preterm babies and to improve their overall health, aiming at reducing the burden on families, caregivers, and the health sector budget worldwide.
Pediatric Strokes: Types, Risk Factors, Symptoms, Treatments, and Diagnosis Amar Taksande, Anugya Taksande, Aashita Malik Journal of Pediatrics Review, 2025 Background: Pediatric strokes, or acute cerebrovascular events in children aged 28 days to 18 years, are serious medical conditions that can result in substantial morbidity and mortality.Objectives: This study aimed to review the types, risk factors, symptoms, treatments, and diagnosis methods of pediatric strokes.Results: Strokes in children can be categorized into various groups based on their specific characteristics; whether the stroke is ischemic or hemorrhagic, whether it affects the arterial or venous systems, and whether it involves the anterior or posterior circulation of the brain.Ischemic strokes may stem from arterial blockages or venous sinus thrombosis, while hemorrhagic strokes are typically caused by spontaneous bleeding within the brain tissue or subarachnoid space.In younger children, symptoms are often nonspecific, making early recognition challenging.Magnetic resonance imaging (MRI), especially with diffusion-weighted sequences, is essential for promptly identifying ischemic strokes.Accurate and timely diagnosis relies heavily on clinical awareness.Currently, treatments such as tissue plasminogen activator (tPA) and mechanical thrombectomy are not routinely recommended in pediatric cases due to insufficient evidence supporting their safety and effectiveness.Conclusions: Pediatric healthcare providers must be familiar with the wide range of potential causes and complications associated with stroke in children.
Congenital Nasal Lipomeningocele in an Infant: A Case of Cerebrospinal Fluid Rhinorrhea with Impending Meningitis Shruti Ankathi, Jayant Vagha, Amar Taksande, Revat Meshram International Journal of Nutrition Pharmacology Neurological Diseases, 2025 Congenital nasal lipomeningocele is a rare craniofacial anomaly caused by a skull base defect resulting in herniation of meninges and adipose tissue into the nasal cavity. It may present with nasal obstruction, cerebrospinal fluid (CSF) rhinorrhea, and an increased risk of meningitis, necessitating timely evaluation and intervention. We report the case of an 8.5-month-old female infant with a progressively enlarging congenital nasal mass and persistent CSF rhinorrhea since birth. Magnetic resonance imaging (MRI) confirmed a lipomeningocele in the left nasal cavity with a skull base defect. Due to signs of impending meningitis, lumbar puncture and intravenous antibiotics were promptly initiated. Surgical intervention was deferred to allow weight and hematologic optimization, thereby reducing perioperative risks such as recurrent infections and anesthesia-related complications. This case highlights the importance of early imaging, infection control, and multidisciplinary planning to prevent severe neurologic outcomes in infants with congenital nasal anomalies.
A fatal case of brain abscess in a child with tetralogy of fallot: a rare and devastating complication Shruti Ankathi, Jayant Vagha, Amar Taksande, Revat Meshram International Journal of Nutrition Pharmacology Neurological Diseases, 2025 Brain abscess is a rare but severe complication in children with cyanotic congenital heart disease, particularly tetralogy of fallot (TOF). Due to the risk of paradoxical embolism and infective endocarditis, these patients are highly susceptible to central nervous system infections, which can rapidly progress to life-threatening complications. We report the case of a 6-year-old male child with a known diagnosis of TOF who presented with persistent high-grade fever, headache, and neurological deterioration. Initial investigations revealed leukocytosis, thrombocytopenia, and positive blood cultures for methicillin-resistant Staphylococcus aureus . Imaging confirmed a ruptured brain abscess with resultant ventriculitis and hydrocephalus. Despite emergency neurosurgical intervention, including external ventricular drainage and abscess evacuation, the child developed worsening septic shock, disseminated intravascular coagulation, and refractory seizures. Despite intensive medical and surgical management, the patient succumbed to multiorgan failure. This case underscores the importance of early recognition of neurological complications in cyanotic congenital heart disease. Delayed diagnosis and the aggressive nature of sepsis in immunocompromised children significantly increase mortality. A multidisciplinary approach involving early imaging, targeted antibiotic therapy, and timely surgical intervention is crucial for improving outcomes in high-risk cases.
Juvenile systemic sclerosis with rapid progression and multisystem involvement in an adolescent Swati Khapekar/Majarikar, Revat Meshram, Dinesh Hinge, Amar Taksande, Mangesh Deshmukh, Abhijit Kumar Agrawal BMJ Case Reports, 2025 Juvenile systemic sclerosis (JSSc) is a rare, progressive autoimmune disorder that can affect the skin, musculoskeletal system, gastrointestinal tract, lungs, heart, kidney and endocrine glands. Clinical presentation varies depending on organs involved and may include oesophageal dysmotility, interstitial lung disease, pulmonary hypertension, constrictive pericarditis, patchy myocardial fibrosis and glomerulonephritis with considerable morbidity and mortality. We are reporting a rare case of JSSc with multisystem involvement in an adolescent male. He presented with a 5-month history of polyarticular arthritis, skin thickening and hypopigmented skin lesions. After 2 months of treatment with methotrexate, he reported minimal improvement in joint pain, swelling and skin thickening, followed by worsening after self-cessation of treatment due to varicella zoster infection. His condition progressed with worsening skin thickening, polyarticular arthritis, joint contractures, restricted mobility, interstitial lung disease and dysphagia.
Study of Ventilator-associated Pneumonia in the Pediatric Intensive Care Unit of a Tertiary Care Hospital Dinesh V. Hinge, Madhumati Otiv, Amar Taksande, Revat J. Meshram Journal of Datta Meghe Institute of Medical Sciences University, 2025 Introduction: Ventilator-associated Pneumonia (VAP) is the most prevalent nosocomial infection and the primary cause of morbidity and death for pediatric intensive care unit (PICU) patients. Even though aseptic methods, antimicrobial treatment, supportive care, and preventative measures including the VAP bundle, early feeding and cuffed endotracheal tubes, mortality due to VAP as an independent cause is still very high. The study is to determine the microorganisms responsible, risk factors, incidence, and mortality of VAP was the study’s main objective. Methods: This was a prospective and cross-sectional study. The patient information was recorded on a verified predesigned pro forma. Duration of hospital stay, ventilator days, intubation, mortality, tracheostomy, and organisms were isolated from minibroncoalveolar lavage noted. After 48 h of mechanical ventilator was observed for any sign and symptoms of VAP. We defined the VAP as per the Clinical Pulmonary Infection Score for suspecting VAP and confirm the diagnosis culture and chest X-ray. Results: Among the 95 ventilated children, seven (7.36%) were found to have VAP. Acinetobacter Baumannii (4.2%) and Klebsiella pneumonia (2.1%) were the most prevalent Gram-negative bacteria grown. Ventilation days (P = 0.026), PICU stay (P = 0.041), and reintubation (P = 0.05) were the major risk factors for the VAP. Mortality was 14.3% in children with VAP and non VAP 26.2% (P = 0.719). Conclusions: Compared to other Indian centers, this study’s VAP incidence was lower. Three major risk factors for the VAP were length of stay in the PICU, number of ventilation days, and intubation. According to this analysis, there was no significant relation between VAP and mortality.
Optimizing premature nutrition: An updated review of human and donor milk fortification and its implication in growth and neurodevelopmental outcomes Ashwini Lakra, Mahaveer Singh Lakra, Ishani Arora, Heena Bhandekar, Amar Taksande, Roshan Prasad, Mayur Wanjari Chulalongkorn Medical Journal, 2025 Poor growth in intrauterine and extrauterine life and inadequate protein supplementation in babies during the first weeks of premature babies are linked to long-term growth failure and poor brain development. The calorie requirements of premature newborns cannot always be fulfilled, even with routine and traditional fortification. This is because traditional fortification procedures rely on the presumed well-known composition of human milk rather than the calculated one. The protein content of mothers' milk of preterm babies varies, decreases with breastfeeding duration, and differs with donor human milk being preserved in milk banks for a long duration. Newer fortification techniques are needed to solve these problems of protein and micronutrient undernutrition, which have led to the concept of "lacto-engineering." This review article focuses on feeding practices, traditional and targeted fortification, bedside human milk content analysis, lactoengineering, and its implications in the neonatal intensive care unit (NICU), particularly in developing countries.
Editorial: Recent advances with orthostatic intolerance/tachycardia in children and adolescents: international perspectives Amar Taksande Frontiers in Pediatrics, 2025 Huynh P et al. (9) conducted a systematic clinical review examining the available pharmacological treatments for pediatric POTS. Although no FDA-approved therapies exist for this age group, his analysis suggested that medications such as ivabradine, midodrine, beta-blockers, and fludrocortisone may provide symptom relief in selected cases. However, authors also noted that pediatric treatment decisions are often extrapolated from adult data, and called for dedicated pediatric trials. Taken together, these studies highlight the growing consensus that pediatric POTS is a multi-system condition with autonomic, immunologic, psychological, and possibly genetic components. They also reflect an international effort to refine the diagnostic process, develop predictive tools, and personalize therapy. Importantly, the need for multidisciplinary care is emphasized, spanning pediatric cardiology, neurology, immunology, mental health, and education systems.The psychosocial impact of OI in youth is another recurring theme. Adolescents with POTS often experience stigma, delayed diagnosis, and school disruption. Innovative solutions, such as school-based reconditioning programs and family-centered education, show promise in addressing these challenges and improving quality of life. Looking ahead, several research directions are clear. Large-scale longitudinal studies incorporating biological and psychosocial data are needed to better understand the disease trajectory. The development of pediatric-specific diagnostic criteria and evidence-based treatment guidelines remains a top priority. Additionally, wearable digital technologies and machine learning tools may enable earlier recognition and real-time symptom tracking. In conclusion, this Research Topic reflects the international momentum toward improving care for children and adolescents with orthostatic intolerance. The contributions of authors collectively offer new perspectives and practical solutions to a complex and often misunderstood condition. Their work fosters a shared vision: to ensure that every child with OI or POTS receives timely recognition, individualized care, and hope for recovery.
Neonatal umbilical cord infections: Rates, correlates, and nursing mothers' practices for cord care in a hospital Lalit Zatke, Rahul M. Jumle, Amar Taksande, Shubhangi P. Raut Multidisciplinary Reviews, 2025 Infant sepsis, a leading cause of global infant mortality, is often exacerbated by umbilical cord infections. Despite limited data on the prevalence and risk factors for umbilical cord infections in India, potentially harmful cord care practices remain prevalent among nursing mothers. This study examines the prevalence, risk factors, and maternal behaviors contributing to neonatal umbilical cord infections at a tertiary hospital in western India. A hospital-based cross-sectional study was conducted between March and June 2024, involving 240 newborns aged 2–14 days admitted to the neonatal intensive care unit. Umbilical cord infections were evaluated based on the World Health Organization’s criteria, including discharge, redness, or swelling of the umbilical stump. Maternal and neonatal characteristics, prenatal events, and cord care practices were analyzed using bivariate and multivariate logistic regression with STATA 13.0. The study found that 27.1% of neonates (n = 65) had umbilical cord infections. Among 168 participating mothers, 70% did not adhere to recommended cord care protocols. Hazardous materials, such as ash or saliva, were applied to the umbilical cord by 39.6% of mothers, while 30.4% reported not cleaning the cord at all. Key risk factors for umbilical cord infection included maternal secondary education (adjusted odds ratio [aOR] = 2.1, 95% CI: 1.01–4.18, p = 0.046) and the application of hazardous substances to the cord (aOR = 3.0, 95% CI: 1.37–6.37, p = 0.006). The findings underscore the high prevalence of umbilical cord infections in neonates and the critical role of maternal education and cord care practices. In resource-limited settings, routine neonatal cord examinations and educational interventions during prenatal and postnatal care are essential for reducing umbilical cord infections. Promoting safe cord care practices can significantly mitigate neonatal health risks.
A rare case of cutis aplasia congenita in a newborn Ashwini Lakra, Heena Sudhir Bhandekar, Ishani Arora, Mahaveer Singh Lakra, Amar Taksande Journal of Datta Meghe Institute of Medical Sciences University, 2023
Waardenburg syndrome Iyer Lavanya Ramakrishnan, Amar Taksande Pan African Medical Journal, 2023
Infectious causes of acute encephalitis syndrome hospitalizations in Central India, 2018–20 Babasaheb V. Tandale, Shilpa J. Tomar, Vijay P. Bondre, Gajanan N. Sapkal, Rekha G. Damle, Rahul Narang, Mohiuddin S. Qazi, Padmaja V. Goteti, Manish Jain, Dipty Jain, Vijay Kumar Guduru, Jyoti Jain, Rajesh V. Gosavi, V. Chandra Sekhar, Infectious-Encephalitis-Aetiologies Study-Group, Daya V. Pavitrakar, Vasudha Shankarraman, Shubhangi A. Mahamuni, Asha Salunkhe, Poornima Khude, Pravin S. Deshmukh, Pradeep R. Deshmukh, Abhishek V. Raut, Abhimanyu K. Niswade, Yogendra V. Bansod, Uday W. Narlawar, Manoj Talapalliwar, Pragati Rathod, Punam Kumari Jha, R. Kondal Rao, K. Jyothi, Padmini Soujanya B․, Pavan Kumar M․, Kishore Kumar K․ J․, Amar Taksande, Sunil Kumar, Gargi Mudey, B.S. Yelke, Milind Kamble, Supriya Tankhiwale Journal of Clinical Virology, 2022
Prevalence of vitamin d deficiency in critically ill children and its impact on morbidity Journal of Krishna Institute of Medical Sciences University, 2021
Clinical profile of congenital heart disease in a tertiary care hospital in central India Journal of Datta Meghe Institute of Medical Sciences University, 2016
Renal abscess in a child with sickle cell anemia. Saudi Journal of Kidney Diseases and Transplantation an Official Publication of the Saudi Center for Organ Transplantation Saudi Arabia, 2009
Essential element levels in thalassemia major patients Saudi Medical Journal, 2008