Vusumuzi Ngonidzashe Hove
Scientific Researcher, Pharmaceutical Sciences and Medicinal Chemistry · University at Buffalo
Research Interests
Medicinal Chemistry, PK/PD modeling, Cancer Research
Biography
Vusumuzi Ngonidzashe Hove is a medicinal chemistry researcher and pharmaceutical scientist with a focus on clinical oncology. His research involves investigating the therapeutic efficacy, ADME properties, and toxicity of pharmacologic agents (in vitro and in vivo) using pharmacokinetic/pharmacodynamic (PK/PD) modeling. Another aspect of his work includes identifying clinically relevant drug-drug interactions (DDIs) to inform future regulatory studies on drug disposition. Additionally, he has explored the use of oxime ligands for Fe(III) MRI contrast agents and for sensing Fe(III) and Fe(II). Hove pursued his undergraduate and graduate studies at the University at Buffalo, earning a Bachelor’s degree in Chemistry and two Master of Science degrees in Medicinal Chemistry and Pharmaceutical Sciences. He was awarded the Professor Emeritus Dr. Thomas J. Bardos Scholarship, presented by the University at Buffalo School of Pharmacy and Pharmaceutical Sciences.
Education
• St. George's College, Harare, Zimbabwe (2003-2008) • Bachelor’s Degree in Chemistry (Cum Laude with Distinction) (2010-2014), University at Buffalo, Department of Chemistry • Master of Science (MS) Degree in Medicinal and Pharmaceutical Chemistry (2016-2019), University at Buffalo, Department of Chemistry • Master of Science (MS) Degree in Pharmaceutical Sciences (2019-2023), The University at Buffalo School of Pharmacy and Pharmaceutical Sciences • Ph.D. Degree in Pharmaceutical Sciences (2019-present), The University at Buffalo School of Pharmacy and Pharmaceutical Sciences
Recent Scopus Publications
- Influence of Tyrosine Kinase Inhibition on Organic Anion Transporting Polypeptide 1B3-Mediated Uptake
Links
- ORCID https://orcid.org/0009-0007-6880-7440
- Google Scholar https://scholar.google.com/citations?user=Ujivrh4AAAAJ
- Scopus https://www.scopus.com/authid/detail.uri?authorId=57684577300
- Personal Weblink https://linktr.ee/vusumuzihove