Romano Silvestri
University La Sapienza - Dept Chemistry and Drug Technologies · Prof. Romano Silvestri
Research Interests
The research projects are mainly focused on the drug design and synthesis of new biologically active chemical entities in the areas of antitumor, antiviral or SNC drugs. The drug design is based on molecular models performed by the internal computaional unit....
Biography
Prof. Romano Silvestri is Full Professor of Medicinal Chemistry at the Sapienza University of Rome, Italy. He graduated cum laude from Sapienza University and completed his PhD studies in Pharmaceutical Sciences by the same University. Since being recruited to the Department of Pharmaceutical Studies, he became Assistant Professor (1991-1998) and Associate Professor (1998-2010). In 2008 he moved to Department of Drug Chemistry and Technologies, and in 2010 became Full Professor. In 2015 was visting professor at Emory University, Department of Chemistry, Atlanta, USA (prof. Dennis Liotta), and in 2016 at King’s College, London (UK).
Education
983 B.S. cum laude in Pharmacy 1989 Ph.D., Pharmaceutical Sciences 1991-1998 Assistant Professor 1998-2010 Associate Professor 2010- Full Professor 2012- Director of School in Hospital Pharmacy
Recent Scopus Publications
- Superparamagnetic iron oxide nanoparticle-driven 3-aroyl-1,4-diarylpyrrole nanocomposites (ARDAP@SPION-PEI) mediate renal cancer cell PANoptosis by regulating chromatin accessibility
- Correction to “Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer”
- 4-(5-Chloro-3-(3,4,5-trimethoxybenzoyl)-1H-indol-1-yl)benzenesulfonamide: A Novel Polypharmacology Agent to Target Carbonic Anhydrase IX and XII With Improved Selectivity, Wnt/β-Catenin Signaling Pathway, and P-Glycoprotein
- Metabolism, a Blossoming Target for Small-Molecule Anticancer Drugs
- Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer
Links
- ORCID https://orcid.org/0000-0003-2489-0178
- Scopus https://www.scopus.com/authid/detail.uri?authorId=7005023671
- Personal Weblink https://romanosilvestri.it